How Long to Cook Chicken Breast in the Oven Food.. Web 35 to 40 minutes for large bone-in, skin-on chicken breasts cooked in a 375 degrees F oven How do I tell when chicken breast is done cooking? We’d be remiss not.

Web In general, bone-in, skin-on thighs with skin will take 45 to 50 minutes to roast in a 350-degree F oven. The factors that may influence the timing are what you’re baking.